Etiology of Chocolate Toxicosis in Dogs
Theobroma cacao is the scientific name for the chocolate plant.
The tree grows pods that carry the seeds, which are about 40-50% fat.
Chocolate is derived from roasted seeds.
What makes chocolate toxic?
The primary toxic principles in chocolate are
Theobromine and caffeine are readily absorbed from the gastrointestinal tract and widely distributed throughout the body. They are metabolized in the liver with enterohepatic recirculation.
LD50 of Theobromine is 250-500 mg/kg of body weight
Half life is 17.5 hours
LD50 caffeine in the dog varies from 110 to 200 mg/kg of body weight
Half life is 4.5 hours
Cocoa bean + fat (cocoa butter) + sugar +/- milk +/- other ingredients = Chocolate
Theobromine Content by Chocolate
Helpful Tips to determine Theobromine dose
Written by: Cynthia, CVT Candidate